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__ Credits and Accreditation Credits AMA PRA Category 1 Credits (16.50 hours), American Academy of Physician Assistants (AAPA) Category 1 CME (16.50 hours), American Association of Nurse Practitioners (AANP) Contact Hours (16.50 hours), American Nursing Credentialing Center (ANCC) CE Credits (16.50 hours), Interprofessional Continuing Education (IPCE) CE Credits (16.50 hours) Accreditation In support of improving patient care, the University of California, San Francisco Office of CME is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team

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FOXO4-DRI causes nuclear exclusion of active p53 and induces apoptosis in senescent TM3 Leydig cells Immunofluorescent staining showed elevated levels of Ser15-phospho-p53 in the nucleus of senescent TM3 Leydig cells (Figure 5A)